Recurrence of primary sclerosing cholangitis in pediatric liver transplant recipients
Veena L. Venka, Sarangarajan Ranganathan, George V. Mazariegos, Qing Sun, Rakesh Sindhi
Abstract
Purpose: There is little detailed clinical data on rPSC after LTx in children. Our purpose was to describe patient characteristics in children who experienced rPSC after LTx to identify potential risk factors for recurrence.
Methods: Clinical information of pediatric patients transplanted for PSC was retrospectively reviewed, and variables related to the pre-transplant diagnosis of PSC and post-transplant variables were abstracted. Variables studied include CMV/EBV status, early/late rejection, induction regimen, immunosuppression in the first year, steroid-resistant rejection, diagnosis of inflammatory bowel disease (IBD), and HLA markers commonly associated with PSC. A diagnosis of rPSC was made based on radiographic features, histology or both . . . To read further, please click on the title.
Veena L. Venka, Sarangarajan Ranganathan, George V. Mazariegos, Qing Sun, Rakesh Sindhi
Abstract
Purpose: There is little detailed clinical data on rPSC after LTx in children. Our purpose was to describe patient characteristics in children who experienced rPSC after LTx to identify potential risk factors for recurrence.
Methods: Clinical information of pediatric patients transplanted for PSC was retrospectively reviewed, and variables related to the pre-transplant diagnosis of PSC and post-transplant variables were abstracted. Variables studied include CMV/EBV status, early/late rejection, induction regimen, immunosuppression in the first year, steroid-resistant rejection, diagnosis of inflammatory bowel disease (IBD), and HLA markers commonly associated with PSC. A diagnosis of rPSC was made based on radiographic features, histology or both . . . To read further, please click on the title.
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