Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease
Ashwin N. Ananthakrishna, Andrew Caga, Vivian S. Gainer, Su-Chun Chen, Tianxi Cai, Peter Szolovits, Stanley Y. Shaw, Susanne Churchill, Elizabeth W. Karlson, Shawn N. Murphy, Isaac Kohan, Katherine P. Liao
Abstract
Introduction: Primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) frequently co-occur. PSC is associated with increased risk for colorectal cancer (CRC). However, whether PSC is associated with increased risk of extraintestinal cancers or affects mortality in an IBD cohort has not been examined previously.
Methods: In a multi-institutional IBD cohort of IBD, we established a diagnosis of PSC using a novel algorithm incorporating narrative and codified data with high positive and negative predictive value . . . To read further, please click on the title.
Ashwin N. Ananthakrishna, Andrew Caga, Vivian S. Gainer, Su-Chun Chen, Tianxi Cai, Peter Szolovits, Stanley Y. Shaw, Susanne Churchill, Elizabeth W. Karlson, Shawn N. Murphy, Isaac Kohan, Katherine P. Liao
Abstract
Introduction: Primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) frequently co-occur. PSC is associated with increased risk for colorectal cancer (CRC). However, whether PSC is associated with increased risk of extraintestinal cancers or affects mortality in an IBD cohort has not been examined previously.
Methods: In a multi-institutional IBD cohort of IBD, we established a diagnosis of PSC using a novel algorithm incorporating narrative and codified data with high positive and negative predictive value . . . To read further, please click on the title.
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