Abstract:
Background: The natural history of pediatric-onset primary sclerosing cholangitis (PSC) and overlap with autoimmune hepatitis (PSC/AIH) is poorly known.
Objective: The aim of this study was to evaluate the clinical outcome of patients with pediatric-onset disease in a tertiary referral center.
Methods: We traced 33 patients (median age at diagnosis 16 years), with PSC or PSC/AIH in cholangiography and liver histology diagnosed between December 1993 and 2011, at Helsinki University Hospital. Diagnostic procedures and long-term follow-up were reassessed until the end of December 2013.
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United European Gastroenterology Journal 0(0) 1–8
Author(s) 2015
Reprints and permissions: sagepub.co.uk/journalsPermissions.nav DOI: 10.1177/2050640615616012 ueg.sagepub.com